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  • A Culture of Inquiry
    • Discover Rutgers Research
    • Part of America's Research Engine
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    • Social Responsibility
    • Global Reach
    • Recent Awards
  • Areas of Research
  • Researcher Support
    • Get Started
    • Find Funding
      • Pivot Funding Opportunities Database
      • Limited Submission Opportunities
      • Internal Research Funding Opportunities
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      • Explore Core Facilities
      • Become a Core Facility
      • Core Facility Support
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      • Export Control
      • Human Subjects Protection Program & IRBs
      • Institutional Animal Care and Use Committee
      • Research Integrity
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      • Protect Your Innovation
      • License and Commercialize
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      • Secure Funding
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Lab Mouse eating food

Gnotobiotic Core

Managed by Animal Care, the gnotobiotic core at Rutgers University provides investigators with the ability to work with germ-free and SPF mice. Currently the core maintains a germ-free colony with C57BL/6 GF mice and Swiss Webster mice.

Our germ-free mice are completely free of exogenous, bacterial, fungal and viral microorganisms. To ensure they remain free of all exogenous microbes, our germ-free mice are housed in isolator cages and are routinely monitored. These mice are ideal for the study of the microbiome. The gnotobiotic core also provides investigators with a laboratory that contains a biosafety cabinet and incubator for experimental needs.

Housing

We have four Allentown Sealed Positive Pressure racks that house up to 48 cages each. These cages enable a germ-free environment at the cage level. The isolator cages are great for experiments as each cage provides its own individual isolated clean micro-environment.  Each cage has its own supply of clean air which is filtered through a HEPA filter.  The sterility of each cage is tested every two weeks. We have flexible film isolators available for larger mouse colonies and breeding.

Technical Services

Our gnotobiotic core provides the following types of technical services to researchers as per their protocol needs:

  • colony management and breeding of germ-free and SPF mice
  • injections
  • bleeding
  • identification
  • fecal collection
  • tissue collection for genotyping
  • sterility testing
  • sterile supplies for experiments
  • health monitoring
  • animal husbandry services

Professional Services

Training is available in the following two areas:

  • hands on training using the isolator cages, isolators, and biosafety cabinet
  • hands on training tailored to the lab's needs

Contact

If you have questions regarding the above listed technical or professional services, please contact Amanda Bumber at amanda.bumber@rutgers.edu or call  973-972-9231.

For overall facility inquiries, please contact Dr. LaTisha Moody at lvm34@research.rutgers.edu

Documents

Please note: All documents require a Net-ID login to access.

Gnotobiotic Rates

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