TechAdvance

Learn more about our recently-funded TechAdvance and TechXpress projects. 

Purnima

Our objective is to optimize an inhibitor of the malaria-causing parasite, Plasmodium. We will use structure-guided design to optimize the molecule’s potency against its target kinase. The resulting medicinal chemistry program will yield highly potent and selective inhibitors of Plasmodium suitable for further development of an anti-malarial drug.

Gene Therapy for Spinal Cord Injury

This technology is a virus-based gene therapy for the treatment of spinal cord injury (SCI). The treatment dramatically improves locomotor behavior in a mouse model of SCI by promoting the generation of new neurons for the re-establishment of damaged neural circuits and reducing the glial scar formation at the lesion site.