Blue organic light-emitting diodes (OLEDs) used in displays and lighting technologies have significantly lower efficiency and stability compared with green and red OLEDs. This project will improve blue OLED efficiency and operational stability by increasing light extraction and reducing degradation pathways in the organic semiconductor emissive layer.
This project aims to develop an autonomous navigation system for wheelchairs, enhancing user independence and safety while reducing caregiver workload. It targets individuals with mobility impairments, elderly users, and those with progressive conditions, using system-level design of sensors, navigation, and control technologies for safe navigation in various environments.
Our objective is to optimize an inhibitor of the malaria-causing parasite, Plasmodium. We will use structure-guided design to optimize the molecule’s potency against its target kinase. The resulting medicinal chemistry program will yield highly potent and selective inhibitors of Plasmodium suitable for further development of an anti-malarial drug.
Development of an alternative separation technology based on adsorptive separation which will significantly reduce the energy input and lower the cost associated with the generation of polymer-grade propylene.
This technology is a virus-based gene therapy for the treatment of spinal cord injury (SCI). The treatment dramatically improves locomotor behavior in a mouse model of SCI by promoting the generation of new neurons for the re-establishment of damaged neural circuits and reducing the glial scar formation at the lesion site.
Development of small molecules inhibitors of Keap1-Nrf2 PPI as chemopreventive and therapeutic agents for the treatment of ulcerative colitis