A team of Rutgers researchers merged their ideas and technology with the support of research mentors to get the needed funds for developing a novel device capable of detecting the presence of viruses like SARS-CoV-2 in one’s breath.
The team is developing a novel, first-in-class, orally-available drugs efficacious against tuberculosis and non-tuberculous mycobacterial lung infections. The candidates, RifaAAPs, are active against drug-susceptible, drug-resistant, multi-drug-resistant, and extensively-drug-resistant strains, have lower resistance emergence than current drugs, have higher sterilizing activity than current drugs, and have additive activity in combination with current drugs.
Globally, there are 800,000 new cases of hepatocellular carcinoma (HCC) per year. Treatments are marginally effective today. The team developed a CD147-CAR-NK-based immunotherapy for HCC by re-engineering NK cells to target the specific HCC cell marker CD147, and thereby kill the HCC effectively and safely.