1T MRI - Magnetic Resonance Imager
(Aspect Imaging/Scintica Inc.)

Description

• 3D quantitative image analysis
• Spatial resolution: 100um
• Inflammation +/- contrast agents
• Soft tissue / organs organ morphometry (in vivo / ex vivo)
• High-resolution mouse brain coil
• Gadolinium & Nanoparticle contrast agents

Applications

• Lung Edema
• Breast Cancer / Micro-metastases in the Liver & Lung
• Brain / Spinal Cord - Structure & Lesions
• Dynamic Contrast Enhanced Imaging (DCE-MRI)
• Muscle Mass in Atrophic Limbs

IVIS Lumina X5
(Perkin Elmer)

Description

• Fluorescence / Bioluminescence / Radio-isotopic
• X-ray acquisition will co-register probe signals to anatomical landmarks
• >40 Ex/Em filter combinations

Applications

• Tumor Location / Metastasis
• Migration of GFP-labeled Stem Cells
• Necrosis / Apoptosis in TBI
• Fluorescent / Bioluminescent Cells
• Fluorescent-based ELISAs

 Ultra-High Frequency Ultrasound System
(Vevo2100, VisualSonics)

Description

• High resolution transducers (35-50um)
• Non-invasive / real-time / pre-clinical
• Anatomical & functional endpoints
• Pulsed-Wave / Color Doppler

Applications

• Echocardiography with VevoStrain Analysis
• Blood Flow Velocity / Vascularity
• Flow Turbulence / Vessel Elasticity
• Soft Tissue / Organ Morphometry
• Limb Perfusion Using MicroMarker^TM Contrast Bubbles
• Wound Healing

Albira PET/CT Imaging System
(Carestream/Bruker)

Description

• 3D PET & CT “X-ray” imaging
• PET spatial resolution: 700um
• CT spatial resolution: 90um
• Anatomical & Metabolic Endpoints
• Living Animals / Biological Samples / Biomaterials
• PET tracers are commercially available

Applications

• Lung Injury in Mice & Rats
• Bone Mineral Density
• Body Composition / Obesity Models (Fat / Muscle / Bone)
• Regional Glucose Uptake in Tumors & Brains
• Fluoride Incorporation in Models of Bone Remodeling/Resorption
• Biomaterials / Devices / Computer Components

SkyScan 1272 nanoCT Scanner
(MicroPhotonics/Bruker)

Description

• Ultra-High Resolution 3D Computed Tomography
• Spatial resolution: 350nm
• Maximum sample size: 6cm³
• Numerous contrast agents available

Applications

• Bone Ultrastructure & Mineral Density
• Teeth & Caries
• Human Hair
• Fish Eggs / Embryos
• Grasses & Botanical Specimens
• Diatom & Coral Substructures
• Heating & Cooling Stages

SkyScan 1172 microCT Scanner
(MicroPhotonics/Bruker)

Description

• High-resolution 3D Computed Tomography
• Spatial resolution: 4um
• Sample size: 6cm³
• Numerous contrast agents available
• Located at a Satellite Imaging Facility in Newark NJ

Applications

• Teeth & Caries
• Bone Ultrastructure & Mineral Density
• Rat & Mouse Embryo Development
• Biomaterials