1T MRI - Magnetic Resonance Imager
(Aspect Imaging/Scintica Inc.)

MRI Machine


 

 

 

 

Description

  • 3D quantitative image analysis
  • Spatial resolution: 100um
  • Inflammation +/- contrast agents
  • Soft tissue / organs organ morphometry (in vivo / ex vivo)
  • High-resolution mouse brain coil
  • Gadolinium & Nanoparticle contrast agents

Applications

  • Lung Edema
  • Breast Cancer / Micro-metastases in the Liver & Lung
  • Brain / Spinal Cord - Structure & Lesions
  • Dynamic Contrast Enhanced Imaging (DCE-MRI)
  • Muscle Mass in Atrophic Limbs

FxPro Optical/X-ray Imager
(Carestream/Bruker)

Optical Imager

 

 

 

 


Description

  • Fluorescence / Bioluminescence / Radio-isotopic
  • X-ray acquisition will co-register probe signals to anatomical landmarks
  • >40 Ex/Em filter combinations

Applications

  • Tumor Location / Metastasis
  • Migration of GFP-labeled Stem Cells
  • Necrosis / Apoptosis in TBI
  • Fluorescent / Bioluminescent Cells
  • Fluorescent-based ELISAs

 

 Ultra-High Frequency Ultrasound System
(Vevo2100, VisualSonics)

Ultrasound Machine

 

 

 

 


Description

  • High resolution transducers (35-50um)
  • Non-invasive / real-time / pre-clinical
  • Anatomical & functional endpoints
  • Pulsed-Wave / Color Doppler

Applications

  • Echocardiography with VevoStrain Analysis
  • Blood Flow Velocity / Vascularity
  • Flow Turbulence / Vessel Elasticity
  • Soft Tissue / Organ Morphometry
  • Limb Perfusion Using MicroMarkerTM Contrast Bubbles
  • Wound Healing

Albira PET/CT Imaging System
(Carestream/Bruker)

PET/CT Machine

 

 

 

 


Description

  • 3D PET & CT “X-ray” imaging
  • PET spatial resolution: 700um
  • CT spatial resolution: 90um
  • Anatomical & Metabolic Endpoints
  • Living Animals / Biological Samples / Biomaterials
  • PET tracers are commercially available

Applications

  • Lung Injury in Mice & Rats
  • Bone Mineral Density
  • Body Composition / Obesity Models (Fat / Muscle / Bone)
  • Regional Glucose Uptake in Tumors & Brains
  • Fluoride Incorporation in Models of Bone Remodeling/Resorption
  • Biomaterials / Devices / Computer Components

SkyScan 1272 nanoCT Scanner
(MicroPhotonics/Bruker)

nano CT Machine

 

 

 

 


Description

  • Ultra-High Resolution 3D Computed Tomography
  • Spatial resolution: 350nm
  • Maximum sample size: 6cm3
  • Numerous contrast agents available

Applications

  • Bone Ultrastructure & Mineral Density
  • Teeth & Caries
  • Human Hair
  • Fish Eggs / Embryos
  • Grasses & Botanical Specimens
  • Diatom & Coral Substructures
  • Heating & Cooling Stages

SkyScan 1172 microCT Scanner
(MicroPhotonics/Bruker)

micro CT Machine

 

 

 

 

Description

  • High-resolution 3D Computed Tomography
  • Spatial resolution: 4um
  • Sample size: 6cm3
  • Numerous contrast agents available
  • Located at a Satellite Imaging Facility in Newark NJ

Applications

  • Teeth & Caries
  • Bone Ultrastructure & Mineral Density
  • Rat & Mouse Embryo Development
  • Biomaterials