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Established in statute in 2016, the New Jersey Integrated Population Health Data (iPHD) project aims to promote research that informs improvements in the health, safety, security and well-being of New Jersey residents and the efficiency of state government programs. It achieves this aim by integrating state administrative data sources and providing a process for researchers to apply for and receive data to address questions of importance to New Jersey.

The iPSC Organoid Core Facility will serve as a core resource, providing researchers within the School of Arts and Sciences (SAS) and the broader Rutgers community with access to cutting-edge human organoid technologies.  Human organoids are advanced, three-dimensional (3D) cell culture systems that mimic the structure and function of human organs, offering invaluable models for studying human development, disease mechanisms, drug discovery, and personalized medicine.  The iPSC Organoid Core Facility will leverage the Keck Center's expertise, support its collaborative research goals, and contribute to its mission by providing specialized services, training, and fostering innovation.  Initial service offerings will focus on organoid production for varying durations and hands-on training, with plans for expansion based on emerging needs and technological advancements.

The Mason Gross Documentary Film Lab partners with scientists, artists, researchers, and community leaders within the university and around the world to create dynamic nonfiction films that reach a large audience. Uniquely creative and intentionally interdisciplinary, the lab team produces professional broadcast-ready documentaries while involving students at every level of production.

The Materials Science Department occupies over 60,000 square feet of research laboratories including multiple capabilities available for users on a fee-for-service basis.

The Metabolic Phenotyping Core Facility provides investigators with services to comprehensively assess metabolism in rodents. This is particularly relevant if one is interested in understanding the role of genes or drugs in controlling metabolism and given the huge cost of the obesity and diabetes epidemic, this has potential relevance to many investigators at Rutgers who do not work on metabolism but may have stumbled upon a metabolic phenotype that may potentially have relevance for obesity and diabetes.

We provide advice on experimental design and metabolic phenotyping capabilities such as Indirect calorimetry, body composition, metabolic turnover studies, and hyperinsulinemic-euglycemic clamp analysis in live animals, which includes data analysis and interpretation.  Do not hesitate to contact us if you are considering using our services.

This shared resource pushes the frontiers of tumor metabolism measurements and provides Rutgers Cancer Institute members with easy, cost-effective access to these capabilities. The overarching objective is to enable scientific discoveries that significantly impact cancer diagnosis and therapy.

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The microbiome analysis lab offers genome characterization of complex samples to allow organism identification.

The Molecular and Genomics Informatics Core is designed to provide bioinformatics research services to members of the Rutgers community as a whole and industry collaborators.

The mission of the Molecular and Genomics Informatics Core is to support cutting edge researchers by providing expertise in high-throughput computational analyses. This is to be provided by utilizing up-to-date pipelines for expediting standard workflows, and implementing custom bioinformatics analyses to accommodate the myriad of solutions for academic research. MaGIC will also emphasizes training opportunities by providing remote bioinformatics learning tools, project support and assistance on request, and regular courses.

Services Provided

Whole Genome Sequencing analysis: Variant analysis; De novo assembly

Transcriptome sequencing analysis: Differential gene expression; Pathway analysis

Single cell transcriptome sequencing analysis: Base single cell analysis; Hash-tagged single cell analysis; CITE-seq single cell analysis

Epigenetic sequencing analysis: ChIP-Seq differential peak analysis; ATAC-seq differential peak analysis

Amplicon Sequencing Analysis: Unique amplicon quantification; 16s Metagenomics sequencing analysis; VDJ sequencing diversity analysis

Custom services to include: Hourly consultations; Tool/pipeline development; Web interface development

Anticipated Future Services: Integration of metabolomic and proteomic data analysis; Statistical support for large data set analyses

The Molecular Design and Synthesis Core focuses on the design and synthesis of small molecule probes to investigate new biology. In collaboration with other biomedical scientists, these probes are used to interrogate biological pathways to create preliminary data for grant applications as well as to design molecules for diagnostic and therapeutic use. The core has established research collaborations with biotech companies and Rutgers investigators.

Our current capabilities include: Molecular Design through interpretation of SAR by experienced medicinal chemists; Computer Assisted Drug Discovery and virtual screening; Synthesis of a wide variety of chemotypes (heterocycles/chiral synthesis) as crystalline solids or lyophilized salts, 98% purity; Instrumentation including microwave reactors, LC/MS, analytical and preparative HPLC, NMR and X-ray structure determination.

Our core staff also have experience in cGMP Active Pharmaceutical Ingredients process development and management of API production using an outsourcing approach for Phase 1 to Phase 2 production.

The Natural Products and Bioanalysis Core provides botanical and food product authentication, adulteration, botanical integrity, nutraceuticals, food quality and safety, metabolism, bioavailability and PK studies of natural products, metabolomics and proteomic studies using state-of-the-art analytical instrumentation. Our core also focuses on basic and applied foods, flavor and aroma chemistry and product quality control.