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Rutgers Research Logo Rutgers Research Logo
  • A Culture of Inquiry
    • Discover Rutgers Research
    • Part of America's Research Engine
    • Renowned Faculty
    • Social Responsibility
    • Global Reach
    • Recent Awards
  • Areas of Research
  • Researcher Support
    • Get Started
    • Find Funding
      • Pivot Funding Opportunities Database
      • Limited Submission Opportunities
      • Internal Research Funding Opportunities
    • Core Services
      • Explore Core Facilities
      • Become a Core Facility
      • Core Facility Support
    • Research Compliance
      • Animal Care
      • Conflict of Interest
      • Export Control
      • Human Subjects Protection Program & IRBs
      • Institutional Animal Care and Use Committee
      • Research Integrity
    • Commercialize Your Innovation
      • Innovation Ventures Forms and Policies
      • Protect Your Innovation
      • License and Commercialize
      • Launch a Startup
      • Secure Funding
      • Available Technologies
      • Rutgers Startup Portfolio
    • Find a Research Partner
    • Additional Resources
      • Research Administration Handbook
      • Proposal Development Resources
      • eResearch Systems
      • Training
      • Researcher FAQs
  • About
    • About Office for Research
    • Our Leadership Team
    • Our Units
      • Research & Sponsored Programs
      • Research Financial Services
      • Research Development
      • Research Contract Services
      • Human Subjects Protection Program & IRBs
      • Innovation Ventures
      • Entrepreneurship Partnerships
      • Animal Care
      • Core Services
      • Office of Advanced Research Computing
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  • HealthAdvance
  • HealthAdvance Funded Projects

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HealthAdvance Funded Projects

Explore the latest projects funded through our funding platform that aims to speed up the translation of biomedical discoveries into commercially viable diagnostics, devices, therapeutics and tools to improve health and patient care. 

COVID19 illustration  - breathalizer
COVID-19

Rutgers Researchers Receive Award to Develop Rapid Sensor to Detect COVID-19 and Other Infectious Diseases within a Person’s Breath

A team of Rutgers researchers merged their ideas and technology with the support of research mentors to get the needed funds for developing a novel device capable of detecting the presence of viruses like SARS-CoV-2 in one’s breath.

  • HealthAdvance Fund®
Visual description of A Novel Method of Generating Live-Attenuated, Replication-Defective DNA Viruses for Vaccine Development
HealthAdvance Fund

A Novel Method of Generating Live-Attenuated, Replication-Defective DNA Viruses for Vaccine Development

The long-term goal of this project is to develop a vaccine using centanamycin for DNA viruses where no drug or vaccine is available. Our study offers an attractive opportunity to develop chemically-attenuated live viruses as vaccines for the prevention and treatment of DNA viral infections.

Visual description of Magnetic Nanoparticle-Assisted Non-Viral CRISPR-Cas9 for Advanced Genome Editing
HealthAdvance Fund

Magnetic Nanoparticle-Assisted Non-Viral CRISPR-Cas9 for Advanced Genome Editing

One of the most critical hurdles to developing CRISPR-based therapies for genetic disorders is the lack of effective delivery systems. To this end, this project aims todevelop a next-generation CRISPR delivery solution for fast and effective genome editing that supports the need for the CRISPR-based drug development market.

Visual description of Nervana technology
HealthAdvance Fund

Cellularized Nerve Remediation Graft (CNRG)

The proposed technology will repair peripheral nerve injuries (PNI) by utilizing a biodegradable biopolymer scaffold enclosing a hydrogel-peptide matrix-based 3Dsystem combined with cultured autologous human cells to augment nerve growth once implanted.

KasA
HealthAdvance Fund

A New Tuberculosis Drug Targeting KasA

Tuberculosis is characterized by 10 million cases and 1.5 million deaths per year. New drugs are needed to reduce treatment duration and to treat drug-resistant infections. We propose a solution based on our preclinical drug lead (JSF-3285) that inhibits the essential ß-ketoacyl synthase and exhibits promising efficacy and safety profiles. 

Knapp Image
HealthAdvance Fund

Small Molecule MIF Inhibitors for the Treatment of Inflammatory Bowel Disease

We have identified potent small molecule MIF inhibitors that reduce inflammation-associated cytokines in blood cell and mouse assays, and simultaneously exhibit favorable drug likeness properties including oral availability. They hold promise for the treatment of human inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn’s disease.

Ganapathy-Pierce-picture1
HealthAdvance Fund

Novel Short-Wave Infrared Guided Pre-clinical Screening for Personalized Cancer Therapy With NanoInk Imaging System (NIS)

This project aims to advance nanoparticle-based contrast agents for pre-clinical imaging of tumors in small animals.  The project focuses on (i) scaling up contrast agent synthesis, (ii) assembly of a prototype imaging system, and (iii) proof of concept studies to monitor tumor growth and response to therapy.

3D Illustration: 360-degree spherical panorama view inside biofilm of antibiotic resistant bacteria
HealthAdvance Fund

Surface Functionalization Against Microbial Infections and Biofilms

The prevention of microbial adhesion and biofilm formation on medical device/tissue interfaces is an urgent and unmet need. Thi surface functionalization technology, which is specifically effective in preventing biofilm formation on medical devices, such as implants, aims to address this critical healthcare problem.

Cellular level image
HealthAdvance Fund

Development of Cryptococcus Vaccine Against Invasive Fungal Infections

The research team is developing a Cryptococcus fungal vaccine (HK-fbp1) that has shown cross protection against multiple major invasive mycoses, including Cryptococcus species, Aspergillus fumigatus, and Candida albicans. Its protection remains effective against Cryptococcus and Aspergillus in certain immunocompromised hosts, such as CD4 T cell-depleted mice, a condition mimicking AIDS patients.

Rutgers Shield Logo
HealthAdvance Fund

Developing BMPR2 Inhibitors and Methods of Treating Cancer and Cognitive Defects

Aberrant expression of bone morphogenetic proteins (BMP) has been shown to promote age-related diseases including cancer and Alzheimer’s disease. The research group has developed small molecular inhibitors targeting a BMP receptor that has never been targeted before, aiming to develop this novel class of compounds into a drug for the treatment of cancer and Alzheimer’s disease.

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