Eusebio Pires

Eusebio (EZ) Pires has a great passion for impact-creating biomedical research, demonstrated by the 17 years of his academic professional life focusing on translation and commercialization research. At Innovation Ventures, he leads the efforts for Rutgers Technology Marketing and Business Development. He works very closely with licensing managers and Rutgers inventors to strategically identify business partners for their technologies and at the same time he engages with potential industry partners, building new and fostering existing relationships.

Eusebio earned his BS in Biochemistry & Zoology from St. Xavier’s College in Mumbai, followed by an MS in Biochemistry from the University of Mumbai. After receiving his PhD from the University of Mumbai, he moved to the University of Virginia in Charlottesville, where he developed and led a cancer immunotherapy program. Eusebio also holds an MBA (Focus area: Strategy, Operations and Leadership) from the University of Virginia’ Darden School of Business, and during this time, he was trained in Healthcare Process Improvement & Lean Methodologies. He is also a certified Executive Professional Coach.

1. Naturally Occurring Anti-Albumin Antibodies Are Responsible for False Positivity in Diagnosis of Autoimmune Premature Ovarian Failure. Eusebio S Pires, Priyanka Parte, Perveen Meherji, Shagufta Khan and Vrinda Khole. Jour Histochem & Cytochem. 2006 April, 54 (4): 397- 405.
2. Specific and Sensitive Immunoassays Detect Multiple Anti-Ovarian Antibodies in Women with Infertility. Eusebio S Pires, Pervin K. Meherji, Rama R. Vaidya, Firuza R. Parikh, Manish N. Ghosalkar and Vrinda V. Khole. Jour Histochem & Cytochem. 2007 December, 55(12): 1181-90. 
3. Altered expression of progesterone receptors in testis of infertile men. Shadaan Abid, J Gokral, A Maitra, P Meherji, S Kadam, Eusebio Pires & Deepak Modi. Reprod Biomed Online. 2008 August, 17(2):175-84. 
4. A ‘block’ in the road to fertility: autoantibodies to an immunodominant heat shock protein 90- in human ovarian Autoimmunity. Eusebio S Pires and Vrinda V Khole. Fertil Steril. 2009 October, 92(4):1395-1409. 
5. Anti-ovarian antibodies: specificity, prevalence, multiple antigenicity and significance in human ovarian autoimmunity. Eusebio S Pires and V Khole. Current Paradigm of Reprod Immunol, 2009:159-190. Research Sign Post publish house. 
6. Multiplicity of molecular and cellular targets in human ovarian autoimmunity: an update. Eusebio S Pires. Jour Assis Reprd Genet. 2010 September; 27(9):519-524.* 
7. Can anti-ovarian antibody testing be useful in IVF-ET clinic? Eusebio Pires, Firuza Parikh, Purvi Mande, Shonali Uttamchandani, Sujata Savkar & Vrinda Khole. Jour Assis Reprd Genet. 2011 Jan, 28(1):55-64 
8. Anti-HSP90 autoantibodies in sera of infertile women identify a dominant, conserved epitope EP6 (380- 389) of HSP90 Protein. Eusebio S Pires, Asmita Choudhury, Susan Thomas and V Khole. Reprod Biol & Endocrinol. 2011 Feb, 9:16. 
9. Oocyte specific oolemmal SAS1B involved in sperm binding through intra-acrosomal SLLP1 during fertilization. Monika Sachdev, Arabinda Mandal, Sabine Mulders, Laura C. Digilio, Subbarayalu Panneerdoss, Viswanadhapalli Suryavathi, Eusebio Pires, Kenneth L. Klotz, Laura Hermens, María Belén Herrero, Charles J. Flickinger, Marcel van Duin, John C. Herr. Developmental Biology 2012 363:40–51. 
10. Validation of novel candidate biomarkers for diagnosis of ovarian autoimmunity. Vrinda Khole, Purvi Mande, Asmita Choudhary and Eusebio Pires. Advances in developing affordable in vitro molecular diagnostics, 2012: 139-151. Yashraj research foundation and Mahatma Gandhi Mission University. 
11. SAS1B Protein [Ovastacin] Shows Temporal and Spatial Restriction to Oocytes in Several Eutherian Orders and Initiates Translation at Primary to Secondary Follicle Transition. Eusebio S Pires, Callie Hlavin, Ellen Macnamara, Adey Ishola-Gbenla, Christa Doerwaldt, et al. Develop Dynamics 2013, 242: 1405-26. 
12. Membrane associated cancer-oocyte neoantigen SAS1B/ovastacin is a candidate immunotherapeutic target for Uterine tumors. Pires, Eusebio, D’Souza, R., Needham, M., Herr, A., Jazaeri, A., Li, H., Stoler, M., Anderson-Knapp, K., Thomas, T., Mandal, A., Gougeon, A., Flickinger, C., Bruns, D., Pollok, B., & Herr, J. Oncotarget (2015), 6(30), 30194-30211.* 
13. Consider anti-ovarian antibody testing for ART: a parameter to improve the success rate of your clinic! Eusebio S Pires. Austin Journal of Invitro Fertilization (2015). Volume 2(3):1-5.* 
14. The unmysterious roles of HSP90: ovarian pathology and autoantibodies. Eusebio S Pires. The role of heat shock Proteins in reproductive system development and function. Adv in Anat, Embryo and Cell Biol 2017, 222: 29-44. Springer Publications.*
15. Characterization of SAS1B/Ovastacin mAbs reveals potential diagnostic properties. Eusebio S Pires, Julien Guh, Ryan D’Souza, Farah Shah, Aratara Nutcharoen, Summer Nguyen, Omar Raza, Jagathpala Shetty, Bhupal Ban, Charles Flickinger, and late John Herr. (In submission).* 
16. Evaluation of SAS1B as a target for antibody-drug conjugate therapy in the treatment of pancreatic cancer" by Kiley Knapp, Eusebio Pires, Sara Adair, Arabinda Mandal, Anne M. Mills, Walter Olson, Craig Slingluff Jr., J. Thomas Parsons, Todd W. Bauer, Timothy Bullock, and John Herr. Oncotarget (2018), 9, 8972-8984. * 
17. Heat Shock Proteins: moonlighting roles in human reproduction. Eusebio S Pires*. Regulation of Heat Shock Protein Responses. Heat Shock Proteins, vol 13. Springer, Cham 
18. SAS1B, a biomarker for oocyte quality: origin and functions. Eusebio S Pires*. (Invited review for Jour Assis Reprd Genet, in preparation).