Natural Products and Bioanalysis Core Services
Getting Started
The Natural Products and Bioanalysis Core offers bioanalytical, bioavailability, metabolomics and proteomics support using state-of-the-art analytical instrumentation in botanical and food product authentication, adulteration, botanical integrity, and food quality.
Random non-targeted compound and metabolite profiling and proteomics are achieved using an Agilent 1290 Infinity II UHPLC (Agilent Technology, Palo Alto, CA, USA) system interfaced with an Agilent 6546 Quadrupole Time-of-Flight Mass Spectrometry (UHPLC-QTOF/MS) with an electrospray ionization (ESI) source.
MassHunter Workstation software (version B.10.00 Profinder) processes data obtained by UHPLC–QTOF in MS full scan mode. For targeted metabolomic studies, an Agilent 1290 Infinity II UHPLC with 6470 Triple Quadrupole MS (UPLC-QQQ/MS) is used to determine range of metabolites in biological samples to support animal and clinical studies.
Aromatic volatile compounds and fatty acid analysis is conducted using a Shimadzu TQ8040 GC with Triple Quadrupole MS (GC-QQQ/MS), NCI, Mass spectral libraries, databases, workstation, with a static Headspace Analysis AOC-6000 System with autosampler.
Hemp & Cannabis Analytics
Our new hemp analysis lab provides analytics and potency testing using an Agilent 1220 LC with UV detection for quantitation of cannabinoids, including total THC and total CBD in support of research and industry needs.
Additionally, our core facility includes several analytical labs equipped to conduct stability testing, accelerated ageing and metabolomics, available to Rutgers faculty, students, and industry.
Grant Support
The Natural Products and Bioanalysis Core activities are supported by user fees and with the integration of this core into grants and consortium projects. The Core provides consultations on experimental design, nature of samples needed for analysis (quantity and preparation of samples) and will conduct analysis in concert with faculty and graduate student users. The Core assists in developing new protocols as well as in running routine analyses. Our Core works with faculty, staff, and students to generate pilot data for research grant submissions and can serve as the analytical core in applications to DOD, DOE, EPA, NIH, NSF, USDA, USAID, and more, supporting faculty grant preparation.
